Table 2.
Change in LVEF and Cardiac Biomarkers from Baseline
| Study Timepoint | Change in LVEF (%)a | p-value | Change in hsTnI (pg/ml)a | p-value | Change in BNP (pg/ml)a | p-value | |
|---|---|---|---|---|---|---|---|
| Visit 2 | 3.5 weeks (+/− 1 week) |
−1.9 (−3.2, −0.5) |
0.007 | −8.1 (−18.3, 2.1) |
0.123 | 21.2 (−23.8, 66.2) |
0.361 |
| Visit 3 | 15 weeks (+/− 2 weeks) |
−0.3 (−1.8, 1.2) |
0.714 | −3.7 (−14.6, 7.2) |
0.510 | −8.4 (−57.3, 40.4) |
0.737 |
| Visit 4 | 33 weeks (+/− 2 weeks) |
0.1 (−1.6, 1.8) |
0.933 | −6.3 (−18.3, 5.7) |
0.308 | 6.9 (−48.0, 61.7) |
0.807 |
a
Mean absolute change from baseline, with 95% CI; Analyses performed with linear mixed effects model with random intercept