Table 3.

Severe hypoglycemia rate per 1000 person half-years by quintile of predicted risk and range of risk scores, by site.

16-variable model
	Development cohort, Kaiser Permanente Colorado		Validation cohort, Kaiser Permanente Northwest		Validation cohort 2, HeathPartners
Risk quint iles	Observed severe hypoglycemia rate per 1000 person half-years	Range of risk scores	Observed severe hypoglycemia rate per 1000 person half-years	Range of risk scores	Observed severe hypoglycemia rate per 1000 person half-years	Range of risk scores
1	1.0	0.036–0.206	1.3	0.020–0.066	0.3	0.024–0.069
2	2.2	0.206–0.318	2.5	0.066–0.096	0.8	0.069–0.102
3	5.6	0.318–0.527	5.2	0.096–0.157	2.4	0.102–0.168
4	12.3	0.527–1.052	11.5	0.157–0.318	6.6	0.168–0.336
5	52.6	1.052–39.574	42.6	0.318–11.070	31.0	0.336–10.169
6-variable model
1	1.4	0.024–0.106	1.6	0.007–0.034	0.7	0.010–0.033
2	3.1	0.106–0.158	3.3	0.034–0.049	1.4	0.033–0.048
3	6.0	0.158–0.246	5.6	0.049–0.074	2.7	0.048–0.075
4	12.0	0.246–0.442	11.1	0.074–0.134	6.3	0.075–0.140
5	50.9	0.442–14.356	40.1	0.134–3.405	29.1	0.140–2.911

Risk quintiles were based on exponentiation of the linear scores. Results are averaged across the 5 imputed datasets. We randomly selected one six-month observation period per person, calculated the observed and predicted risk, repeated this process 1,000 times, and then pooled the 1,000 estimates to provide the summary estimates.