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. Author manuscript; available in PMC: 2017 Aug 4.
Published in final edited form as: Clin Cancer Res. 2017 Mar 17;23(15):4233–4241. doi: 10.1158/1078-0432.CCR-16-1209

Figure 1.

Figure 1

A: Representative parametric R2* map (range: 0 – 100 s-1, axial orientation) calculated for a CALR HNSCC xenograft, with the tumor ROI delineated in blue. R2* time series (B, C) were used to calculate corresponding power spectra (E, F) and tested for the presence of non-random fluctuations. Significant non-Gaussian R2* fluctuations (white voxels in binary maps D), in the frequency range of 0-0.005 Hz were spatially mapped (chi-square test: at least one coefficient above P = 0.05, B – D).