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. 2016 Dec 22;2:16037. doi: 10.1038/npjsba.2016.37

Table 3. 20 survival mechanisms that can be either up- or downregulated.

Biological mechanism Up Down Total
Reactome class A1 rhodopsin like receptors 8 8 16
Homeostatic process 7 8 15
Reactome G alpha I signaling events 8 7 15
Reactome gpcr ligand binding 11 7 18
Regulation of developmental process 6 9 15
Kegg cytokine cytokine receptor interaction 6 8 14
Negative regulation of developmental process 6 6 12
Regulation of signal transduction 6 6 12
Regulation of multicellular organismal process 7 6 13
Reactome peptide ligand binding receptors 10 6 16
Regulation of biological quality 11 6 17
Positive regulation of immune response 5 12 17
T cell activation 5 12 17
Reactome hemostasis 5 11 16
Regulation of cell proliferation 5 11 16
T cell differentiation 5 10 15
Biocarta NKT pathway 5 9 14
Cytokine activity 5 8 13
Cytokine binding 5 8 13
Kegg regulation of actin cytoskeleton 5 8 13

The table shows 20 frequent biological mechanisms across combinations of survival markers that can be either up- or downregulated depending of the particular case.