Skip to main content
. Author manuscript; available in PMC: 2017 Jul 19.
Published in final edited form as: Biochemistry. 2016 Dec 20;56(1):179–188. doi: 10.1021/acs.biochem.6b00884

Figure 3. Closing of the N-terminal domain.

Figure 3

Ribbon representation of the superposed monomers of the G-6-P bound activated state (green), yGsy2-R580A/R581A/R583A basal state (magenta, pdb code: 3NAZ), yGsy2-R589A/R592A inhibited state (cyan) and UDP.G trapped activated state (yellow, pdb code: 4KQM). The arrow points in the direction of the N-terminal domain closure, which is towards the C-terminal domain. The helical extensions (α15 and α16) that form the majority of the tetramic interface within each monomer was used to generate the superpositions.