Figure 1.
Co-infusion of ANA-12 attenuated the increase in mean arterial pressure following ICV Ang II. A) Mean arterial blood pressure as measured by telemetry over the course of the experiment. B) Change in MAP relative to baseline (days −3 to −1) in early (days 3–5) and late (days 9–11) periods. C) Heart rate over the course of the experiment. D) Change in HR relative to baseline in early and late periods of ICV infusion. a, p < 0.05 vs. Vehicle; b, p < 0.05 vs. Ang II.