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One compartmental pharmacokinetic analysis of free PPT and Celludo in BALB/c mice. t½: Half-life. AUC: Area under the curve from 0-240 h. Cl: Clearance. Vd: Volume of distribution. C0: plasma drug concentration at starting time point. MRT: Mean residence time.
| Celludo | PPT | |
|---|---|---|
| ti/2 (h) | 11.64 | 0.66 |
| AUC (μg*h/mL) | 45633.70 | 4.91 |
| CI (mL/h) | 0.08 | 80.94 |
| Vd (mL) | 1.33 | 77.46 |
| C0 (μg/mL) | 2717.00 | 5.16 |
| MRT(h) | 16.80 | 0.96 |
