Table 5. List of the host proteins which were shown to have significantly increased or decreased expression (≥ 2- or 0.5-fold) in rabbits with convalescent E. cuniculi disease.

Are shown in this table the 115-tagged proteins that significantly changed only in the 45 rabbits with convalescent condition consistent with past E. cuniculi infection.

Protein identification	Fold change	Known function	Chromosome	Gene name (GenBank®)	Access. number (UniProt®)	Subcellular location	Theoretical MW (kDa)	Calc. pI	Protein score (Sequest®)	No. unique peptide(s)	No. aa	% Seq. coverage
SET domain bifurcated 2	0.2	transport and cell organization and biogenesis (DNA binding, protein binding, metal ion binding); metabolic process (catalytic activity)	IX	SETDB2	G1TX00	Nucleus (chromosome)	81.8	8.0	5.1	1	719	3.2
DEAH (Asp-Glu-Ala-His) box polypeptide 29	0.3	metabolic process (catalytic activity); transport (RNA binding; nucleotide binding)	XI	DHX29	G1U383	Mitochondrion	105.6	8.2	8.3	2	1.366	3.4
Keratin 1	0.5	defense response; metabolic process; regulation of biological process; response to stimulus (structural molecule activity)	IV	KRT1	G1U9I8	Nucleus; membrane; blood microparticle; extracellular exosome, extracellular matrix; keratin filament	64.2	8.5	49.8	1	611	14.8
Uncharacterized protein	2.3	Transport		N/A	G1U0V3	Membrane	66.5	6.6	16.9	1	595	4.4
Ig gamma chain C-region	2.2	Defense and transport (protein binding)		N/A	P01870		35.4	8.3	37.6	2	323	24.5
Immunoglobulin heavy-chain variable region	3.7	Defense and transport (protein binding)		N/A	Q6B726		10.3	8.3	8.2	2	97	39.2
Nudix hydrolase 11	4.3	metabolic process (catalytic activity)		NUDT11	G1TGZ5		19.1	6.4	7.5	1	170	3.5

Abbreviations: aa, Amino acids; Access., Accession; calc., Calculated;

*, homologous protein; kDa, Kilo dalton; MW, Molecular weight; N/A, Not available; No, Number; pI, Isoelectric point; Seq., Sequence.