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. 2017 Jul 19;12(7):e0180484. doi: 10.1371/journal.pone.0180484

Table 5. The 69 novel RNA editing sites identified in the protein-coding genes of U. reniformis mtDNA.

For a complete list of the 147 editing sites identified by the RNAseq approach please refer to S4 Table.

Gene mtDNA Codon Codon position Amino acid Editing level (%)
Position Strand From To From To
nad1
(4 sites)		 99048 + (exon 1) CUA UUA 1 L L 18
99201 + (exon 1) CCG UCG 1 P S 88
344481 + (exon 3) CCC CCU 3 P P 33
726995 - (exon 5) AAC AAU 3 F N 63
nad2
(5 sites)		 297295 - (exon 2) CCA CUA 2 P L 92
463531 + (exon 4) UUC UUU 3 F F 18
463653 + (exon 4) CCG CUG 2 P L 81
465022 + (exon 5) UCC UUC 2 S F 70
465030 + (exon 5) CUC UUC 1 L F 64
nad3
(1 site)		 20810 - CCA CUA 2 P L 92
nad4
(3 sites)		 578975 + (exon 3) CUA UUA 1 L L 36
579324 + (exon 3) CCA CUA 2 P L 94
581798 + (exon 4) ACC ACU 3 T T 93
nad5
(5 sites)		 260779 - (exon 2) GCC GCU 3 A A 29
260950 - (exon 2) AUC AUU 3 I I 20
261311 - (exon 2) GCC GUC 2 A V 75
261673 - (exon 2) ACC ACU 3 T T 25
261677 - (exon 2) CCG CUG 2 P L 92
nad6
(2 sites)		 300266 - CCA CUA 2 P L 93
300273 - CCC UCC 1 P S 90
nad7
(13 sites)		 711488 + (exon 1) AAC AAU 3 N N 13
712855 + (exon 2) UCU UUU 2 S F 70
713691 + (exon 3) CGU UGU 1 R C 100
713819 + (exon 3) GUC GUU 3 V V 24
713906 + (exon 3) UCC UCU 3 S S 12
714114 + (exon 3) CUU UUU 1 L F 91
715347 + (exon 4) CCU CUU 2 P L 72
715366 + (exon 4) UCC UCU 3 S S 61
715453 + (exon 4) CCC CCU 3 P P 88
715506 + (exon 4) UCU UUU 2 S F 85
715522 + (exon 4) CAC CAU 3 H H 72
715527 + (exon 4) CCA CUA 2 P L 98
715569 + (exon 4) UCU UUU 2 S F 100
nad9
(3 sites)		 497201 + UCU UUU 2 S F 73
497282 + CCA CUA 2 P L 47
497708 + UCU UUU 2 S F 78
cob
(2 sites)		 779528 + UCU UUU 2 S F 92
779794 + CUA UUA 1 L L 86
cox1
(2 sites)		 321763 + (exon 1) ACC ACU 3 T T 89
323181 + (exon 2) CUG UUG 1 L L 96
cox2
(1 site)		 514300 + CUA UUA 1 L L 84
cox3
(1 site)		 558125 + UUC UUU 3 F F 67
atp4
(2 sites)		 285091 + CCC CUC 2 P L 87
285114 + CCG UCG 1 P S 95
atp6
(2 sites)		 810361 - UCC UCU 3 S S 48
810993 - CGU UGU 1 R C 64
atp8
(1 site)		 556640 + UGC UGU 3 C C 84
ccmFc
(3 sites)		 834747 + (exon 1) CAU UAU 1 H Y 63
834901 + (exon 1) CCA CUA 2 P L 77
836320 + (exon 2) CUA UUA 1 L L 32
ccmFn
(1 site)		 488236 - ACC AUC 2 T I 61
rpl5
(4 sites)		 22103 - CCG UCG 1 P S 16
22105 - CCU CUU 2 P L 77
22173 - AUC AUU 3 I I 13
22389 - UCC UCU 3 S S 31
rpl10
(3 sites)		 611859 + ACC ACU 3 T T 35
611934 + CGG UGG 1 R W 41
612084 + UAC UAU 3 Y Y 40
matR
(7 sites)		 102277 + UCC UCU 3 S S 96
103757 + CGC UCG 1 R S 16
103771 + UAC UAU 3 Y Y 75
rps3
(4 sites)		 263919 - (exon 2) CCG CUG 2 P L 97
263864 - (exon 2) UCC UCU 3 S S 48
264252 - (exon 2) CCA CUA 2 P L 15
264811 - (exon 2) CGA UGA 1 R Stop 85
rps4
(1 site)		 267470 - UCC UCU 3 S S 56
rps12
(1 site)		 20376 - CCC CCU 3 P P 11
rps14
(2 sites)		 21929 - UCC UCU 3 S S 21
21974 - CCC CCU 3 P P 17