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. 2017 Jul 19;12(7):e0181176. doi: 10.1371/journal.pone.0181176

Table 2. Respiratory hospital admissions and postnatal dexamethasone exposure.

Respiratory hospital admission n = 88, 21%
N Unadjusted proportions Adjusted proportions 1
Dexamethasone exposure p-value<0.001
No 292 0.15 0.15
Yes 120 0.36 0.35
Difference (95% CI)
Yes vs no 0.20 (0.11, 0.30) 0.20 (0.08, 0.31)
Timing of dexamethasone Overall p-value:
<0.001
Overall p-value:
<0.001
None 292 0.15 0.15
Early 9 0.44 0.48
Late 111 0.35 0.34
Differences (95% CI)
Early vs none 0.29 (-0.04, 0.62) 0.33 (-0.01, 0.66)
Late vs none 0.20 (0.10, 0.30) 0.18 (0.07, 0.30)
No. of courses Overall p-value:
<0.001
Overall p-value:
0.001
0 course 292 0.15 0.15
1 course 76 0.34 0.33
2 courses 31 0.39 0.38
3 courses 13 0.38 0.40
Differences (95% CI)
1 vs 0 courses 0.19 (0.07, 0.30) 0.18 (0.06, 0.30)
2 vs 0 courses 0.23 (0.06, 0.41) 0.23 (0.03, 0.43)
3 vs 0 courses 0.23 (-0.04, 0.50) 0.25 (-0.05, 0.55)
No. of days of exposure Overall p-value:
<0.001
Overall p-value:
<0.001
0 292 0.15 0.15
1–6 24 0.21 0.22
7–12 44 0.41 0.39
>12 51 0.40 0.38
Differences (95% CI)
1–6 vs 0 0.05 (-0.11, 0.22) 0.07 (-0.10, 0.24)
7–12 vs 0 0.25 (0.10, 0.41) 0.23 (0.08, 0.39)
>12 vs 0 0.24 (0.10, 0.38) 0.23 (0.07, 0.39)

1. Adjusted for sex, birthweight z-score, gestational age in weeks, smoking in pregnancy, oxygen dependency at 36 weeks, airleak, patent ductus arteriosus, pulmonary haemorrhage, major neonatal ultrasound abnormality, ventilation group and age at 24 month assessment using multiple logistic regression analysis.