. Author manuscript; available in PMC: 2017 Jul 19.

Published in final edited form as: J Thorac Cardiovasc Surg. 2016 Sep 19;153(1):118–125.e1. doi: 10.1016/j.jtcvs.2016.09.016

TABLE 4.

Assessment of perfusion goals achieved in controls and goal-directed perfusion patients

	Controls	Goal-directed perfusion patients	P value
Crystalloid prime volume (median mL, IQR)	650 (500–1000)	800 (500–1000)	.28
PRBC in prime (%, n)	9.5 (8)	14.8 (13)	.35
Received any mannitol in prime (%, n)	91.7 (77/84)	17.1 (15/88)	<.001
Total phenylephrine administered (median mg ± IQR)	1.5 (0.7–3.25)	0.65 (0.2–2.4)	.001
Heparin drip used in OR	0	50.6 (45/88)	<.001
Nadir temperature on CPB (°C ± SD)	32 ± 3	33 ± 3	.02
Hemoconcentrator used (%, n)	46.4 (39/84)	98.9 (87/88)	<.001
Volume exchanged with hemoconcentrator (median L ± IQR)	2.0 (1.2–3.0)	6.0 (4.3–9.0)	<.001
Nadir Hb on CPB (mg/dL ± SD)	9.0 ± 1.8	8.7 ± 2.0	.46
Nadir pump flow/m² (L/min/m² BSA ± SD)	1.9 ± 0.3	2.4 ± 0.4	<.001
Nadir DO2 (mL O₂/min/m² BSA ± SD)	240 ± 64	302 ± 62	<.001

Complete perfusion records were available for 84 of 88 historical controls and 88 of 88 GDP patients. Bold indicates statistical significance. IQR, Interquartile range; PRBC, packed red blood cell; OR, operating room; CPB, cardiopulmonary bypass; SD, standard deviation; Hb, hemoglobin; DO2, oxygen delivery; BSA, body surface area.