Table 1. Genic loci associated with indices of human-directed social behavior across dogs and wolves.
NA, not applicable.
| Phenotype | Locus ID | SV type |
Position (Mb)* |
β (SE) |
% Variation explained |
P† |
Candidate gene |
| ABS | Cfa6.66 | Deletion | 5.75 | 0.23 (0.09) | 4.45 | 1.38 × 10−4 | GTF2I |
| Cfa6.3 | Insertion | 2.14 | 0.11 (0.07) | 0.56 | 8.12 × 10−4 | WBSCR17 | |
| Cfa6.7 | Deletion | 2.54 | 0.12 (0.07) | 0.62 | 8.89 × 10−4 | WBSCR17 | |
| SIS | Cfa6.66 | Deletion | 5.75 | −27.0 (24.80) | 11.45 | 1.95 × 10−4 | GTF2I |
| Top three principal components (PC model) |
Cfa6.72 | Deletion | 5.90 | 0.04 (0.052), −0.96 (0.57), 1.11 (0.36) |
NA | 4.98 × 10−4 | GTF2IRD1 |
*See table S7 for locus details.
†P values from likelihood ratio test (adjusted significance threshold P = 2.38 × 10−3).