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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Int J Psychophysiol. 2016 Nov 19;115:40–56. doi: 10.1016/j.ijpsycho.2016.11.008

Table 7.

GWAS results for all candidate SNPs producing nominally significant associations (p < 0.05).

SNP Chr Position Gene Alleles MAF r2 Beta SE t-Statistic df p-Value Measure
rs13247338 7 126,090,509 GRM8 C T 0.143 0.998 0.336 0.169 1.99 3428 0.047 Theta-ITPC
rs2299456 7 126,168,766 GRM8 A G 0.160 – 0.040 0.018 2.23 4131 0.026 Delta
rs2402816 7 126,191,176 GRM8 A G 0.382 – −0.675 0.240 −2.81 4158 0.005 Delta-ITPC
rs2299459 7 126,195,368 GRM8 A C 0.216 1.000 −0.050 0.016 −3.15 4131 0.002 Delta
rs1158720 7 126,208,306 GRM8 C T 0.223 0.991 −0.045 0.016 −2.87 4131 0.004 Delta
rs7797602 7 126,287,827 GRM8 C T 0.220 0.997 −0.049 0.016 −3.10 4131 0.002 Delta
rs7797602 7 126,287,827 GRM8 C T 0.220 0.997 −0.568 0.283 −2.01 4158 0.045 Delta-ITPC
rs1074728 7 126,312,844 GRM8 G A 0.459 – −0.026 0.013 −2.01 4131 0.045 Delta
rs1074728 7 126,312,844 GRM8 G A 0.459 – −0.628 0.232 −2.71 4158 0.007 Delta-ITPC
rs4731323 7 126,324,030 GRM8 A G 0.220 – 0.035 0.015 2.30 4131 0.021 Delta
rs1424558 7 136,531,671 CHRM2 C G 0.340 0.997 −0.260 0.125 −2.07 3428 0.038 Theta-ITPC
rs1396862 17 43,902,997 CRHR1 G A 0.204 0.998 0.035 0.016 2.22 3410 0.026 Theta
rs878886 17 43,912,490 CRHR1 C G 0.204 0.998 0.035 0.016 2.22 3410 0.026 Theta
rs878887 17 43,912,582 CRHR1 C T 0.204 0.998 0.035 0.016 2.22 3410 0.026 Theta

Note: Chr is the chromosome on which each SNP is located, while Position is its base pair position (GRCh37/hg19). Gene gives the nearest gene, while Alleles give the major and minor alleles, respectively, and MAF the frequency of the minor allele. r2 is the imputation r2, a measure of imputation quality. If it is not provided, then the SNP was called. Beta is the estimated coefficient from RFGLS, with SE its standard error, t-statistic the test statistic. Measure indicates which time-frequency measure was associated with a given SNP in our data. All SNPs are located in genes, except rs1424558, which flanks CHRM2. The Bonferroni-adjusted p-value threshold was 2.73 × 10−4.