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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Int J Psychophysiol. 2016 Nov 19;115:40–56. doi: 10.1016/j.ijpsycho.2016.11.008

Table 8.

VEGAS gene-based test associations for candidate genes.

Gene Chr N SNPs Start position End position Theta-Fz energy Theta-Fz ITPC Delta-Pz energy Delta-Pz ITPC




Test-statistic p-Value Test-statistic p-Value Test-statistic p-Value Test-statistic p-Value
DISC1 1 543 229,829,183 230,243,641 383.31 0.895 859.68 0.092 636.08 0.333 785.77 0.517
ARID5A 2 46 96,566,190 96,582,098 88.07 0.147 118.18 0.036 10.09 0.980 29.57 0.605
DRD3 3 145 115,330,246 115,380,589 228.56 0.148 212.56 0.190 244.06 0.123 126.91 0.507
GSK3B 3 214 121,028,235 121,295,203 138.55 0.700 222.08 0.408 663.98 0.014 109.84 0.835
MME 3 131 156,280,129 156,384,212 101.98 0.650 67.87 0.910 76.65 0.884 140.82 0.378
FABP2 4 124 120,457,852 120,462,764 40.52 0.859 100.18 0.457 48.84 0.802 9.72 1.000
CNR1 6 137 88,906,303 88,911,775 99.68 0.719 71.53 0.892 84.87 0.821 156.15 0.345
ABCB1 7 228 86,970,883 87,180,500 444.58 0.058 137.49 0.791 229.71 0.401 105.44 0.898
CHRM2 7 293 136,203,938 136,352,311 97.41 0.999 186.34 0.817 252.84 0.586 485.29 0.116
GRM8 7 1338 125,865,887 126,679,664 1077.12 0.702 667.54 0.962 2544.71 0.042 2927.19 0.020
ANXA13 8 209 124,762,214 124,818,828 228.41 0.408 214.90 0.472 278.91 0.211 328.66 0.113
HTR7 10 233 92,490,555 92,607,651 235.46 0.435 386.14 0.182 344.19 0.175 84.82 0.911
BDNF 11 96 27,633,017 27,699,872 193.04 0.078 115.37 0.306 33.08 0.933 52.04 0.787
DRD2 11 202 112,785,526 112,851,211 153.85 0.617 117.38 0.815 176.80 0.525 201.69 0.435
DRD4 11 60 627,304 630,703 105.67 0.132 45.88 0.625 29.95 0.830 68.39 0.338
MYEF2 15 12 46,218,920 46,257,850 4.75 0.465 27.23 0.099 7.46 0.429 12.46 0.289
CRHR1 17 47 41,217,448 41,268,973 272.32 0.001 46.54 0.384 11.79 0.911 53.22 0.311
KCNJ6 21 495 37,918,656 38,210,566 298.26 0.940 289.99 0.939 357.49 0.819 399.33 0.709
COMT 22 146 18,309,308 18,336,530 259.82 0.078 316.40 0.032 89.53 0.812 61.00 0.954

Note: Chr is the chromosome on which each gene is located, NSNPs is the total number of SNPs included by VEGAS within the gene boundary. Its start and end position (using build hg37) are provided as well. The test-statistic for each phenotype is a chi-square statistic. Nominally significant associations (p < 0.05) are italicized. Only one association (bold face and italicized) surpassed the Bonferroni threshold of 2.64 × 10−3: CRHR1 and theta-Fz energy.