Table 2.
Demographic and clinical characteristic of bipolar I disorder subjects experiencing a first manic or mixed episode, divided between those who did and did not respond to lithium at 8 weeks of treatment.
| Characteristic | Bipolar I Disorder Subjects | |
|---|---|---|
|
| ||
| Responders (n=15) | Non-responders (n=5) | |
| Age, years | 17 (3) | 21 (6) |
| Sex, N, (%) male | 7 (47) | 3 (60) |
| Mood state, N (%) manic | 7 (50)a | 3 (60) |
| Psychosis present, N (%) | 3 (21)a | 3 (60) |
| Baseline YMRS, total score | 26 (5) | 22 (3) |
| 8-week YMRS, total scoreb | 6 (4) | 20 (6) |
Note.
a
One responder did not receive a DSM-IV diagnostic code, so beyond the diagnosis of first-episode bipolar I disorder, mood state and psychosis are not known in this case and n = 14.
b
Significant difference, responders v. non-responders (by definition), t(18) = 6.58, p < .001.
Values are mean (SD) unless otherwise stated. YMRS = Young Mania Rating Scale.