Wild-type and syndecan-1 −/− mice underwent laparotomy and hemorrhagic shock followed by resuscitation with either LR or FFP. After 3 hours lungs were homogenized for measurement of A. syndecan2 and B. Sdc4 by ELISA. Data are expressed as mean SEM, n=8 per group with significance indicated by lines over the respective groups. FFP, fresh frozen plasma; LR, lactated Ringer’s; WT, wild type; KO, Sdc1 knockout; HS, hemorrhage shock.