Table 1.
Biomedical nanoparticles developed from a wide variety of materials recently reported for theranostic applications. Nanoparticles with multiple functionalities are listed multiple times.
Noble metals | Other metals | Metal oxides | Semiconductors | Silica | Carbon | Polymers / Liposomes | Proteins | Other materials | ||
---|---|---|---|---|---|---|---|---|---|---|
Imaging | MRI | [40, 55, 157] | [26, 28, 40, 88, 133, 158-161] | [6-12, 26, 28, 40, 118, 121, 123, 133, 158-160, 162-168] | [39-40] | [55] | [40] | [126, 165] | [82, 169-170] | |
PET/SPECT | [16-17, 25, 29-30, 40, 101-102, 142, 171] | [24, 26, 28, 40, 158-159, 172-174] | [24, 26, 28, 40, 158-159, 162, 172-175] | [18, 40] | [20, 27, 34-35] | [40, 109, 136] | [21, 23, 99, 102, 106, 134-135] | [32, 176] | [22, 33, 131-132, 135, 145, 169] | |
CT | [17, 30, 62, 65, 137-139, 142, 171] | [80, 118-120] | [18] | [20, 27, 35] | [62, 80, 138] | [135, 143, 145] | ||||
Optical | [36, 49-50, 52, 55-60, 146, 177] | [36, 108, 117] | [36, 78, 116] | [19, 39] | [34-35, 49-50, 52, 55-60, 156, 177] | [109] | [38, 43, 78, 105, 107, 126-127, 129, 146, 178] | [116, 176] | [145, 169] | |
Photo-acoustic | [62-67] | [79, 88] | [78, 80, 90-91, 93] | [72-73, 83-85] | [92] | [87, 151] | [43, 62, 67-69, 71-73, 75, 78-80, 83-85, 93, 106] | [76] | [74, 77, 81-82, 86, 145] | |
Ultrasound | [78, 165] | [78, 126-127, 165] | ||||||||
Cerenkov | [30, 101-102, 104, 171] | [24] | [24, 98, 103, 162, 175] | [18-19] | [100] | [99, 102, 135] | [98] | [145, 179-180] | ||
Therapy | Drug delivery | [66] | [166] | [92] | [136] | [105-106, 125, 127] | ||||
Gene/siRNA delivery | [146] | [108] | [109] | [99, 105, 107, 146, 178] | ||||||
Immuno-therapy | [101] | [12] | [130] | [129-130] | [181] | |||||
PTT/PDT | [16, 63, 65, 67, 110-113, 146, 157] | [88, 117, 174] | [78, 80, 98, 116, 174] | [73, 83-84] | [100] | [67, 73, 75, 78, 80, 83-84, 129, 146] | [76, 98, 116] | [82, 86, 143] | ||
Radio-therapy | [137-142] | [133] | [116, 118, 133] | [135, 138] | [116] | [143] | ||||
Externally actuated | [114-115] | [118-121, 123] |