Table 2.
Docking and energy calculation results of potent Artemisinin derivatives against plasmepsin-2
| Compounds | Glide score | Glide energy |
|---|---|---|
| A2T (crystal ligand) | −10.895 | −93.678 |
| N30 | −9.224 | −80.836 |
| N32 | −9.051 | −64.257 |
| N39 | −8.342 | −45.534 |
| 12f | −7.889 | −57.929 |
| N8 | −7.458 | −56.81 |
| N47 | −7.04 | −46.242 |
| N1 | −6.159 | −42.097 |
| A53 | −6.09 | −33.931 |
| N2 | −6.008 | −42.762 |
| N31 | −5.732 | −52.009 |
| A54 | −5.097 | −28.057 |
| N45 | −4.714 | −30.696 |
| N3 | −4.432 | −35.244 |
| DHA | −4.011 | −30.894 |
| Deoxy-Artemisinin | −3.904 | −21.788 |
| Artemisinin | −2.795 | −32.612 |
| A62 | −2.326 | −5.349 |