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. 2017 Jul 20;8:277. doi: 10.3389/fneur.2017.00277

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Copyright © 2017 Hesam-Shariati, Trinh, Thompson-Butel, Shiner and McNulty.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variability accounted for (VAF) in muscle synergies. VAF changed little over time; the mean VAF was measured for any given number of synergies and compared between patients for the three levels of motor-function. For each number of synergies, patients with low motor-function had higher VAF compared to the other two groups (p < 0.05). Lower VAF for patients with moderate and high motor-function indicated that the analysis is less able to account for variability of muscle activation because of more movement complexity.