Table 1.
Baseline characteristics.
| Characteristics | Pazopanib (n = 31) | Everolimus (n = 31) | P-value |
|---|---|---|---|
| Age | 68.0 (8.0) | 68.8 (7.9) | P = 0.68 |
| AGE GROUP | |||
| P = 0.59 | |||
| <65 | 12 (38.7) | 10 (32.3) | |
| ≥65 | 19 (61.3) | 21 (67.7) | |
| ECOG | |||
| 0 | 17 (54.8) | 6 (19.4) | P = 0.007 |
| 1 | 10 (32.3) | 22 (71.0) | |
| 2 | 4 (12.9) | 2 (6.4) | |
| 3 | – | 1 (3.2) | |
| KPS | |||
| <80 | 7 (22.6) | 17 (54.8) | P = 0.002 |
| ≥80 | 24 (77.4) | 11 (35.5) | |
| Unknown | – | 3 (9.8) | |
| RISK STATUS MSKCC | |||
| Good | 6 (19.4) | 2 (6.5) | P = 0.30 |
| Intermediate | 21 (67.7) | 22 (71.0) | |
| Poor | 4 (12.9) | 6 (19.4) | |
| Unknown | – | 1 (3.2) | |
| RISK STATUS IMDC | |||
| Good | 6 (19.4) | 2 (6.4) | P = 0.22 |
| Intermediate | 21 (67.7) | 22 (71.0) | |
| Poor | 1 (3.2) | 3 (9.7) | |
| Unknown | 3 (9.7) | 4 (6.4) | |
| METASTASIS SITE | |||
| Lung | 20 (64.5) | 21 (67.7) | P = 0.138 |
| Liver | 7 (22.6) | 12 (38.7) | P = 0.168 |
| Kidney | 14 (45.1) | 9 (29.0) | P = 0.188 |
| Bone | 9 (29.0) | 8 (25.8) | P = 0.775 |
| Other | 13 (41.9) | 17 (54.8)* | P = 0.309 |
*
Four patients had brain metastasis.
ECOG, Eastern Cooperative Oncology Group; KPS, Karnofsky Performance Status; MSKCC, Memorial Sloan-Kettering Cancer Center; IMDC, International Metastatic Renal Cell Carcinoma Database Consortium. Data were presented as mean (standard deviation) for continuous variables or number (frequency) for categorical variables.