Table 1. SCFAs (Acetate, Propionate, Butyrate) production by microbiota in the Gut.
| SCFAs | Pathways/Reactions | Producers | References |
|---|---|---|---|
| Acetate | from pyruvate via acetyl-CoA | Most of the enteric bacteria | Louis P, et al., Nat Rev Microbiol. 2014, 12: 661–72.12) |
| (Representative of species bacteria) Akkermansia muciniphilia, | Rey FE, et al,. J Biol Chem. 2010, 285: 22082–90.13) | ||
| Bateroides spp., Bifidobacterium spp., Prevotella spp., | |||
| Ruminococcus spp. | |||
| Wood-Ljungdahl pathway | Blautia hydrogentrophica, Chrostridium spp., Streptococcus spp. | ||
| Propionate | succinate pathway | Bacteroides spp., Phascolarctobacterium succinatutens, | Louis P, et al., Nat Rev Microbiol. 2014, 12: 661–72.12) |
| Dalister spp., Veilonella spp. | Scott KP, et al., J Bacteriol. 2006, 88: 4340–9.14) | ||
| acrylate pathway | Megasphaera elsdenii, Coprpcoccus catus | ||
| propanediol pathway | Salmonella spp., Roseburia inulinivorans, Ruminocossus obeum | ||
| Butyrate | phosphotransbutyrylase/butyrate kinase route | Coprococcus comes, Coprococcus eutactus, | Duncan SH, et al., Appl Environ Microbiol. 2002, 68: 5186–90.15) |
| Louis P, et al., Nat Rev Microbiol. 2014, 12: 661–72.12) | |||
| butyryl-CoA: acetate CoA-transferase route | Anaerostripes spp. (A, L), Coprococcus catus (A), | ||
| Eubacterium rectale (A), Eubacterium hallii (A, L), Faecalibacterium prausnitzii (A), Roseburia spp. (A) | |||
Citationed from Koh A, et al, Cell 165, 1332–458)
spp., species; (A), acetate is the substrate for producing butyrate; (L), lactate is the substrate for producing butyrate