Table 2. Fecal concentration of individual SCFAs (Acetate, Propionate, Butyrate) by human adults.
| Subjects (n); age | Reported measure | Acetate | Propionate | Butyrate | Total SCFAs | Unit | References | |
|---|---|---|---|---|---|---|---|---|
| Healthy subjects | 10; 21–34 years | Mean (SD) | 218 (99) | 72 (37) | 58.7 (54.5) | 378 (188) | µmol/g dry weight | Whelan K, et al., J Nutr. 2005, 135: 1896–902.20) |
| 20; 20–40 years | Mean (SEM) | 320.3 (24.9) | 97.3 (10.5) | 93.8 (9.13) | 511.4 (41.9) | µmol/g dry weight | Boler BM, et al., Br J Nutr. 2011, 106: 1864–71.21) | |
| 13; 23–58 years | Median (IQR) | 52.2 | 23.2 (13.6–37.3) | 36.8 (5–128) | 119.3 (64.5–197.0) | µmol/g wet weight | Lewis SJ, et al., Gut. 1997, 41: 245–51.22) | |
| 60; 18–24 years | Mean (SEM) | 198.4 (14.2) | 55.2 (4.7) | 50.5 (4.9) | 304.1 | µmol/g dry weight | Lecerf JM, et al., Br J Nutr. 2012, 108: 1847–58.23) | |
| 27; 18–55 years | Mean (SEM) | 35.8 (2.4) | 11.4 (1.2) | 10.0 (1.1) | 61.1 (4.4) | µmol/g | Reimer RA, et al., J Hum Nutr Diet. 2012, 25: 373–7.24) | |
| 12; 18–65 years | Mean (SD) | 48 | 13.98 | 13.31 | 80.91 | µmol/g | Fernando WM, et al., Benef Microbes. 2010, 1: 197–207.25) | |
| 46; 31–66 years | Mean (95%CI) | 44.7 females (39.7, 50.3) | 12.3 females (10.7, 14.0) | 11.7 females (9.8, 14.0) | 69.5 females (61.3, 78.7) | µmol/g | McOrist AL, et al., J Nutr. 2011, 141: 883–9.26) | |
| 58.6 males (49.8, 69.0) | 16.1 males (13.4, 19.5) | 15.4 males (12.1, 19.6) | 90.5 males (76.3, 108) | |||||
| 36 | Median (IQR) | 43.7 (34.0–52.2) | 13.1 (9.2–18.5) | 8.8 (5.2–11.5) | 91.8 (73.1–107.5) | µmol/g | Nemoto H, et al., Dig Dis Sci. 2012, 57: 2955–64.27) | |
| 20; 22–55 years | Mean (SEM) | 42.13 (3.8) | 11.5 (1.2) | 11.28 (1.4) | 67.3 (6.2) | µmol/g | Tiihonen K, et al., Br J Nutr. 2010, 103: 1070–8.28) | |
| 8; 31–59 years | Mean (SD) | NR | NR | NR | 92.7 (33.9) | µmol/g | McOrist AL, et al., Br J Nutr, 2008, 100: 138–46.29) | |
| 20; 23–28 years | Mean (SEM) | NR | NR | NR | 78.5 (6.4) | µmol/g | Hylla S, et al., Am J Clin Nutr, 1998, 67: 136–42.30) | |
| 30 | Mean (SD) | 50.5 (12.6) | 13.6 (5.2) | 14.1 (7.6) | 84.6 (22.9) | mmol/L | Schwiertz A, et al., Obesity. 2010, 18:190–5.31) | |
| Obese subjects | 20; 22–55 years | Mean (SEM) | 47.2 (3.8) | 13.6 (1.3) | 14.7 (1.5) | 78.8 (6.2) | µmol/g | Tiihonen K, et al., Br J Nutr. 2010, 103:1070–8.28) |
| 91 | Mean (SD) | 58.5 (19.1) | 17.6 (7.6) | 18.3 (9.7) | 102 (33.5) | mmol/L | Brinkworth GD, et al., Br J Nutr. 2009; 101: 1493–502.32) | |
| 32; 20–65 years | Mean (SEM) | NR | NR | NR | 34 (6) | mmol/24h | Benassi-Evans B, et al., Mutat Res, 2010; 703: 130–6.33) | |
| 35 over weight | Mean (SD) | 56.0 (18.2) | 18.3 (7.9) | 18.5 (10.1) | 98.7 (33.9) | mmol/L | Schwiertz A, et al., Obesity. 2010, 18: 190–5.31) | |
| 33 obese | 59.8 (18.3) | 19.3 (8.7) | 18.1 (10.0) | 103.9 (34.3) | ||||
Citationed from Verbeke KA, et al., Nutr Res Rev. 28:42–6619)
Mean, the mean value; SD, standard deviation; SEM, standard error of the mean; IQR, interquartile range; 95%CI, 95% confidence limit; NR, not reported.