Table 2. Age- and sex-adjusted incidence (per 1000 person-years) of cardiovascular disease according to non-HDL-C levels by CKD status.
CKD (−) |
CKD (+) |
|||||||
---|---|---|---|---|---|---|---|---|
Serum non-HDL-C levels, mg/dL |
Serum non-HDL-C levels, mg/dL |
|||||||
< 150 | 150–189 | ≥ 190 | p for trend | < 150 | 150–189 | ≥ 190 | p for trend | |
(n = 1,089) | (n = 753) | (n = 431) | (n = 141) | (n = 118) | (n = 98) | |||
Cardiovascular disease | ||||||||
No. of events | 145 | 100 | 74 | 38 | 32 | 33 | ||
Person-years | 17,207 | 12,367 | 7,162 | 1,691 | 1,552 | 1,248 | ||
Age- and sex-adjusted incidence | 10.9 | 11.5 | 13.4 | 0.1 | 16.8 | 20.2 | 22.2 | 0.1 |
Coronary heart disease | ||||||||
No. of events | 53 | 45 | 36 | 16 | 17 | 19 | ||
Person-years | 17,743 | 12,794 | 7,326 | 1,795 | 1,637 | 1,341 | ||
Age- and sex-adjusted incidence | 3.8 | 4.3 | 7.7 | 0.002 | 6.3 | 11.1 | 12.5 | 0.02 |
Stroke | ||||||||
Ischemic stroke | ||||||||
No. of events | 76 | 54 | 34 | 16 | 19 | 13 | ||
Person-years | 17,324 | 12,480 | 7,296 | 1,717 | 1,594 | 1,301 | ||
Age- and sex-adjusted incidence | 5.7 | 7.1 | 5.4 | 0.8 | 6.5 | 11.4 | 7.7 | 0.7 |
Hemorrhagic stroke | ||||||||
No. of events | 27 | 14 | 9 | 10 | 1 | 4 | ||
Person-years | 17,324 | 12,480 | 7,296 | 1,717 | 1,594 | 1,301 | ||
Age- and sex-adjusted incidence | 1.9 | 1.4 | 1.2 | 0.3 | 4.9 | 0.4 | 2.5 | 0.3 |
Abbreviations: CKD, chronic kidney disease; non-HDL-C, non-high-density lipoprotein cholesterol.