Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 19;7:5884. doi: 10.1038/s41598-017-06049-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The SCI-induced reshuffle between GABAergic and glycinergic inhibition in TFNs. (a) Cumulative probability plots for the inter-event interval and the amplitude of sIPSCs (left) and summary of the median frequency and the median current amplitude (right) in TFNs in control and spasticity. (b) Occurrence of the fast (τ < 13 ms) and the slow (τ > 13 ms) inhibitory currents in TFNs in control and spasticity. (c) Examples of the fast inhibitory currents (left) and cumulative probability plots for the current amplitude (right) in TFNs in control and spasticity. The currents are average from 25 fast sIPSCs recorded in 11 TFNs in control (black line) and 53 fast sIPSCs recorded in 11 cells in spastic animals (red line). (d) The amplitude of fast sIPSCs plotted against the correspondent decay constant in TFNs from control and spastic animals. The Spearman correlation coefficients with the Spearman’s non-parametric test significance are indicated. (e) The average balance between synaptic excitation and inhibition of TFNs, estimated as the median frequency of sEPSCs to the median frequency of sIPSCs for each individual TFN in control (n = 10 cells) and spasticity (n = 9 cells). (f) The relative balance between excitatory drive and synaptic inhibition of AFNs and TFNs in control and post-SCI. The Kolmogorov-Smirnov (KS) or the Mann-Whitney U-test significance is indicated.