Table 1.
Baseline characteristics of the cohort
Variable | Total cohort (n = 2606) | Serum ferritin category | |||
---|---|---|---|---|---|
<50 ng/mL (n = 616) | 50–99.9 ng/mL (n = 450) | 100–199.9 ng/mL (n = 635) | ≥200 ng/mL (n = 905) | ||
Age (years) | 64.0 (12.0) | 62.9 (12.0) | 62.7 (12.4) | 64.4 (11.9) | 65.0 (11.7) |
Male (%) | 62.1 | 63.0 | 60.2 | 58.9 | 64.6 |
Years on dialysis (years) | 5.0 (1.6–10.3) | 5.8 (2.2–10.7) | 4.9 (1.30–10.4) | 4.7 (1.2–10.4) | 4.9 (1.5–10.1) |
Diabetes (%) | 38.7 | 33.0 | 39.3 | 38.0 | 42.9 |
Comorbidities of CVD (%) | |||||
CHF | 25.7 | 25.7 | 25.6 | 23.9 | 27.0 |
CAD | 37.5 | 37.0 | 37.3 | 35.0 | 39.6 |
Stroke | 15.2 | 14.1 | 18.4 | 13.1 | 15.9 |
PAD | 20.2 | 17.2 | 20.0 | 19.7 | 22.8 |
Others | 33.7 | 30.4 | 33.1 | 32.1 | 37.4 |
Body mass index (kg/m2) | 21.1 (3.3) | 21.3 (3.3) | 21.1 (3.4) | 21.1 (3.3) | 21.1 (3.3) |
Alb (g/dL) | 3.76 (0.42) | 3.81 (0.41) | 3.76 (0.41) | 3.76 (0.40) | 3.74 (0.43) |
CRP (mg/dL) | 0.12 (0.06–0.37) | 0.12 (0.06–0.31) | 0.10 (0.05–0.30) | 0.10 (0.06–0.31) | 0.15 (0.06–0.50) |
Hb (g/dL) | 10.4 (1.2) | 10.4 (1.3) | 10.5 (1.2) | 10.4 (1.2) | 10.3 (1.2) |
Single pool Kt/V | 1.35 (0.28) | 1.38 (0.27) | 1.34 (0.31) | 1.34 (0.28) | 1.34 (0.28) |
ESA users (%) | 92.0 | 90.0 | 93.2 | 92.0 | 92.7 |
Dose of ESA (103 units/month) | 18.0 (9.0–28.5) | 18.0 (11.3–36.0) | 16.5 (9.8–26.4) | 18.0 (9.0–24.0) | 16.0 (9.0–27.0) |
IV iron user (%) | 30.0 | 24.7 | 32.0 | 30.5 | 32.1 |
Dose of IV iron (mg/month) | 160 (160–320) | 160 (160–320) | 160 (160–480) | 160 (160–480) | 160 (160–240) |
Values for categorical variables are given as percentage; values for continuous variables are given as mean (SD) or median (interquartile range). Dose of ESA was calculated only for ESA users and expressed as recombinant human erythropoietin (epoetin α or ß) using a conversion ratio of 1:200 for darbepoetin α. Dose of IV iron was also calculated only for IV iron users
Alb albumin, Hb hemoglobin, CRP C-reactive protein, CVD cardiovascular disease, CHF congestive heart failure, CAD coronary artery disease, PAD peripheral artery disease, ESA erythropoiesis-stimulating agent, IV intravenous