Table 3.
Associations of serum ferritin categories with all-cause mortality and CVD hospitalization for the total cohort
Outcomes | Ferritin categories (ng/mL) | Univariate analysis | Multivariate analysisa | ||
---|---|---|---|---|---|
HR | 95 % CI | HR | 95 % CI | ||
All-cause mortality | |||||
<50 | 1.58 | 1.05–2.38 | 1.79 | 1.18–2.72 | |
50–99.9 | 1.00 | Referent | 1.00 | Referent | |
100–199.9 | 1.46 | 0.96–2.20 | 1.43 | 0.94–2.18 | |
≥200 | 1.70 | 1.15–2.51 | 1.55 | 1.05–2.29 | |
CVD hospitalization | |||||
<50 | 1.00 | Referent | 1.00 | Referent | |
50–99.9 | 1.47 | 1.15–1.89 | 1.43 | 1.11–1.83 | |
100–199.9 | 1.55 | 1.24–1.94 | 1.53 | 1.22–1.92 | |
≥200 | 1.82 | 1.47–2.24 | 1.72 | 1.39–2.12 |
CRP C-reactive protein, CVD cardiovascular disease, HR hazard ratio, ESA erythropoiesis-stimulating agent, IV intravenous, 95 % CI 95 % confidence interval
aAdjusted for age, sex, years on dialysis, diabetes mellitus, prior CVD, body mass index, albumin, CRP, hemoglobin, and single pool Kt/V, ESA dose, and IV iron dose