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. 2017 Jul 19;7:5861. doi: 10.1038/s41598-017-06221-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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LEfSe analysis of saliva microbiota in caries versus caries-free adolescents. (A) Cladogram generated by LEfSe indicating differences at phylum, class, family and genus levels between the two groups. Each successive circle represents a phylogenetic level. Regions in red indicate taxa enriched in caries affected while regions in green indicate taxa enriched in caries-free subjects. Differing taxa are listed on the right side of the cladogram. (B) Bar graph showing LDA scores.