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. 2017 Jul 19;7:5861. doi: 10.1038/s41598-017-06221-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PLS loading column plot. Mean (95% CI) PLS correlation coefficients for the top 20 taxa associated with having caries and all taxa associated with being caries-free. The PLS model included caries as dependent variable and saliva detected species level taxa, sex, BMI, oral hygiene, and sweet snacking, as the independent block. w describes the PLS weights from the combination of the original variables in the X-swarm and c the same for the Y-swarm. A variable is considered statistical significant when the 95% CI of the correlation coefficient does not include zero.