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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Anal Chim Acta. 2016 Mar 19;921:46–58. doi: 10.1016/j.aca.2016.03.024

Table 4.

Types of isoprostanes quantified in human and mice biological samples using the method described in Section 3.

Biological samples Sample size IsoPs detected
Human plasma 1 mL 15-F2t-IsoP, 15-epi-15-F2t-IsoP, 5-F2t-IsoP, 5-epi-5-F2t-IsoP, 10-F4t-NeuroP, 10-epi-10-F4t-NeuroP, 4(RS)-F4t-NeuroP
Human CSF 600 μL n.d
Mouse Plasma ≥ 200 μL 15-F2t-IsoP, 15-epi-15-F2t-IsoP, 5-F2t-IsoP, 5-epi-5-F2t-IsoP
Mouse Urine ≥ 200 μL Ent 15 (RS) 2,3 dinor 5,6 dihydro 15-F2t-isoP, 15-F2t-IsoP, 15-epi-15-F2t-IsoP, 5-F2t-IsoP, 5-epi-5-F2t-IsoP
Mouse Liver 200 mg 15-F2t-IsoP, 15-epi-15-F2t-IsoP, 5-F2t-IsoP, 5-epi-5-F2t-IsoP, 10-F4t-NeuroP, 10-epi-10-F4t-NeuroP, 4(RS)-F4t-NeuroP
Mouse Brain 200 mg 15-F2t-IsoP, 15-epi-15-F2t-IsoP, 5-F2t-IsoP, 5-epi-5-F2t-IsoP, 10-F4t-NeuroP, 10-epi-10-F4t-NeuroP, 4(RS)-F4t-NeuroP, Ent-7(RS)-F2t-Dihomo IsoP
Mouse Muscle 200 mg 5-F2t-IsoP, 5-epi-5-F2t-IsoP

n.d. not detected; IsoP: isoprostane; NeuroP: neuroprostane