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. 2017 Jul 19;7:5801. doi: 10.1038/s41598-017-06374-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Altered behavior of Pcdh19 mutants in the Porsolt forced swim and tail suspension tests. (a,b) Porsolt forced swim test with male (a) and female (b) mice. (a) Pcdh19 hemizygous male mutants (X⁻Y) showed a significantly higher immobility rate (a) compared to wild-type male mice, whereas heterozygous female mutants (X⁺X⁻) showed a lower immobility rate than wild-type female mice (b). (c,d) Tail suspension test with male (c) and female (d) mice. Both Pcdh19 hemizygous (X⁻Y) and heterozygous female (X⁺X⁻) mutants showed a significantly lower immobility rate compared to wild-type counterparts.