Figure 2.

Forest plots of associations (slopes, 95%CI) of continuous ¹⁸-F-FDG PET biomarkers with continuous B-SIT as the outcome variable. The diamonds represent slopes (estimated change in B-SIT per unit increase in FDG PET standardized uptake value ratio) from general linear models, adjusted for age, sex, education. The solid horizontal lines represent the 95% confidence intervals.

AD signature = an AD signature ¹⁸F-FDG PET SUVR was calculated based on glucose metabolic rates from an AD signature meta-ROI and consisted of the average bilateral angular gyri, posterior cingulate, and inferior temporal cortical ROIs from both hemispheres normalized to pons and vermis uptake.