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. 2017 Jul 19;18:345. doi: 10.1186/s12859-017-1761-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Operon structure inclusion into annotation probability with E. coli. The predicted operon information of E. coli was integrated in PAC values by considering genes on the same operons for NCBI and random annotation