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. 2017 Jul 19;14:138. doi: 10.1186/s12974-017-0913-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Surgery resulted in an increased expression of CB2R in the hippocampus. JWH133 treatment alleviated the surgery-induced upregulation of CB2R in the hippocampus, while AM630 aggravated it. Representative Western blotting bands show the expression of CB2R in the hippocampus 1, 3, and 7 days after surgery (a–c). The expression of CB2R was normalized to that of GAPDH as an internal control (d–f). The data are plotted as the mean ± standard error of the mean for each group (n = 3 per group). *p < 0.05 versus the control group, ^# p < 0.05 versus the surgery group