Table 2.
Metabolic components of the biomass function
| Complex metabolites | • protein, composed of: | |
| ◦ tRNA ligated amino acids (20)* | ||
| • lipid, composed of | ||
| ◦ sphingomyelin* | ||
| ◦ cholesterol | ||
| ◦ phosphatidyl choline | ||
| ◦ phosphatidyl ethanoloamine | ||
| ◦ triacylglycerides* | ||
| ◦ diacyclglycerides* | ||
| ◦ phosphatidyl inositol* | ||
| ◦ phosphatidyl glycerol* | ||
| ◦ acyl phosphatidyl glycerol* | ||
| • reduced and oxidized glutathione* | ||
| • protoheme | ||
| Amino Acids | • alanine | • arginine |
| • asparagine | • aspartate | |
| • cysteine | • glutamate | |
| • glutamine | • glycine | |
| • histidine | • isoleucine | |
| • leucine | • lysine | |
| • methionine | • serine | |
| • phenylalanine | • proline | |
| • threonine | • tryptophan | |
| • tyrosine | • valine | |
| Carbohydrates | • malate* | |
| • α-ketoglutarate* | ||
| Nucleotides | • ATP | • dATP |
| • CTP | • dCTP | |
| • GTP | • dGTP | |
| • UTP | • dTTP | |
| • thiamine diphosphate | ||
| Excreted metabolites | • lactate* | |
| • hemozoin* | ||
| Vitamins | • pyridoxal | |
| • 5-phosphate riboflavin | ||
| Other | • s-adenosyl l-methionine | • putrescine |
| • spermidine | • 2-octaprenyl 6-hydroyphenol | |
| • f-thf | • mthf | |
| • thf | • FAD | |
| • coenzyme-A | • NAD | |
| • water | • Fe2+ & Fe3+ | |
| • NADP | • SO4 | |
| • NH4+ | ||
f-thf = formyl tetrahydrofolate; mthf = methyltetrahydrofolate; thf = tetrahydrofolate
*metabolites that have been added to the iPfal17 and are not present in the biomass function of iTH266