Table 1.
Mean scores (and standard deviations) for demographic and neuropsychological variables obtained at Time 1 by the different study groups: single domain amnestic mild cognitive impairment (sda-MCI), multiple domain amnestic mild cognitive impairment (mda-MCI), and a group with subjective memory complaints without cognitive impairment (SMC).
| Variable | SMC (N = 207) | sda-MCI (N = 46) | mda-MCI (N = 21) | F(2, 271)χ2(2, 274) | Groups comparison (Bonferroni) |
|---|---|---|---|---|---|
| Gender | Men: 30% | Men: 54.3% | Men: 9.5% | ||
| Women: 70% | Women: 45.7% | Women: 90.5% | |||
| Age | 65.30 (8.87) | 69.67 (8.75) | 71.86 (8.43) | F = 8.76*** | sda-MCI, mda-MCI > SMC |
| Range: 50–87 | Range: 52–87 | Range:54–87 | |||
| Years of education | 9.74 (4.47) | 9.41 (4.12) | 9.86 (3.92) | F = 0.12 | |
| Range: 1–22 | Range: 2–20 | Range: 3–18 | |||
| Retest interval | 18.96 (4.54) | 19.32 (6.32) | 21.48 (8.96) | χ2 = 1.01 | |
| MMSE | 28.20 (1.43) | 27.46 (1.76) | 23.33 (1.37) | χ2 = 60.78*** | mda-MCI < sda-MCI < SMC |
| Memory complaints (participant) | 19.18 (4.38) | 19.38 (4.47) | 18.92 (3.37) | F = 0.46 | |
| Memory complaints (informant) | 15.52 (4.20) | 16.82 (4.48) | 16.75 (4.88) | F = 1.78 | |
| Language | 25.70 (2.40) | 25.10 (2.64) | 23.91 (1.83) | F = 12.57*** | SMC, sda-MCI > mda-MCI |
| Attention-calculation | 7.61 (1.54) | 7.46 (1.60) | 5.92 (2.61) | χ2 = 19.83*** | SMC, sda-MCI,> mda-MCI |
| Executive function | 18.40 (4.13) | 16.47 (3.88) | 13.90 (3.19) | F = 14.53*** | mda-MCI < sda-MCI < SMC |
| WMS-III (Immediate auditory memory) | 98.91 (11.52) | 85.91 (10.15) | 82.10 (10.34) | F = 39.96*** | sda-MCI, mda-MCI < SMC |
| WMS-III (Delayed auditory memory). | 111.39 (14.30) | 97.12 (12.74) | 92.70 (12.88) | F = 30.07*** | sda-MCI, mda-MCI < SMC |
| CCI | 0.85 (0.88) | 0.80 (0.90) | 0.76 (0.76) | F = 0.16 | |
| Range: 0–3 | Range: 0–3 | Range: 0–2 |
Gender distribution is indicated with percents. MMSE, Mini-Mental State Examination; WMS-III, Wechsler Memory Scale-Third Edition; CCI, Charlson Comorbidity Index.
***
p < 0.0001.