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Effect of HPV and 8q24.22 knockout on senescence of HeLa cells. (a) Senescence‐associated acidic β‐gal activity detected by Cell Senescence Assay. Wild‐type HeLa cells and HeLa cells with overexpressed SOX6 were detected as negative and positive controls, respectively. The scale value is 400 μm. (b) The quantified analysis of senescence phenotype in four type of HeLa cells shown in 5a. [Color figure can be viewed at wileyonlinelibrary.com]
