Table 1.
Model parameters. All parameters were based on those used in Kopell et al. (2010). Where changes were made the original values from Kopell et al. (2010) are given in bold brackets for comparison. Changes in sodium and potassium conductance and reversal potentials were chosen to produce waveforms closer to those we observed experimentally and were within the ranges used in other similar biophysical modelling studies (Traub et al., 1994; Wang & Buzsaki, 1996; Ermentrout & Kopell, 1998)
| Parameters | Value | Unit | |||
|---|---|---|---|---|---|
| Excitatory cells | Inhibitory cells | ||||
| Number of cells | N pr | 80 | |||
| N in | 20 | ||||
| Capacitance | C | 1 | 1 | μF/cm2 | |
| Conductances | Sodium | gNa | 50 (100) | 35 | mS/cm2 |
| Potassium | gK | 20 (80) | 9 | mS/cm2 | |
| Leak | gL | 0.1 | 0.1 | mS/cm2 | |
| M‐current | gK m | 0.5 | mS/cm2 | ||
| Reversal potentials | Sodium | V Na | 50 | 55 | mV |
| Potassium | V K | −70 (−100) | −90 | mV | |
| Leak | V L | −67 | −65 | mV | |
| M‐current | V Km | −85 | mV | ||
| Synaptic conductances | E to E | g E‐E | 0.5 (0) | mS/cm2 | |
| I to E | g I‐E | 1.5 | mS/cm2 | ||
| I to I | g I‐I | 0.7 (0.5) | mS/cm2 | ||
| E to I | g E‐I | 1.5 (0.5) | mS/cm2 | ||
| Synaptic reversal potentials | V rev | 0 | −80 | mV | |
| Synaptic time constants | Rise time | τ R | 0.1 | 0.3 | ms |
| Decay time | τ D | 3 | 9 | ms | |