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Single pancreatic islet cell analysis using MALDI MS and CE–ESI-MS interfaced with the off-line liquid microjunction extraction system. (A) Representative single-cell MALDI MS profiles of single α and β cells. (B) Corresponding CE–ESI-MS extracted ion electropherograms of the same cells showing signals of amino acids with high intensities and (C) signals of amino acids with lower signal intensities.
