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. 2017 May 30;37(7):1065–1073. doi: 10.1111/liv.13284

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© 2017 The Authors Liver International Published by John Wiley & Sons Ltd

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Liver inflammation and fibrosis score for the evaluation of (A) fibrosis, (B) ballooning, (C) lobular inflammation and (D) activity. (A) There was a significant association between LIF and fibrosis (r _s=.51; P<.0001). The median LIF score could differentiate (B) ballooning grades (LIF 1.2, 2.7 and 3.5 for ballooning grades 0, 1 and 2 respectively (P<.05), (C) lobular inflammation grades (LIF 1.6 vs 2.7 for lobular inflammation grade 0 vs >0) and (D) overall activity (LIF 1.3 vs 3.0 for mild (0‐1) vs significant activity.2, 3, 4 Lines and error bars indicate the median and interquartile range on all graphs [Colour figure can be viewed at wileyonlinelibrary.com]