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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar;2(2):170–179. doi: 10.1016/j.bpsc.2016.12.003

Figure 4.

Figure 4

fMRI results for neural activity during risky vs. safe decision making, and relationship with age. Clusters represent regions that showed a significant group by age interaction effect for risky vs. safe decisions. We found a significant interaction in the middle frontal gyrus and frontal pole, such that controls showed a negative relationship between neural activity and age, whereas patients with NF1 showed increasing neural activity with increasing age. Graphs represent percent signal change. Pearson correlation values: frontal pole: NF1: r=0.60, p=0.01; Controls: r=−0.49, p=0.04; angular gyrus: NF1: r=0.34, p=0.18; Controls: r=−0.76, p<0.01.