Fig. 4.

Quantification of T cells inside and outside lesion core in Study I. Spinal cord sections were immunolabeled for CD3, a pan T cell marker (A, B), and the number of CD3 positive cells inside and outside the lesion was counted in vehicle and gemfibrozil (GEM) treated animals. Tissue sections and lesion cores are outlined. Areas in boxes are shown at high power below cross-sections. There were significantly more CD3+ cells outside the lesion in gemfibrozil treated mice compared to controls (C) (p<0.001). Low power image scale bar=100 µm, high power image scale bar=25 µm.