Table 3.
Effect of PE on cell cycle progression in MCF-7 and MDA-MB-435 cells after 24 h and 48 h exposure.
| Cell line | Incubation time | Cell cycle phases | Control (CT) | 500 μg/mL | 1000 μg/mL |
|---|---|---|---|---|---|
| MCF-7 | 24 h | G0/G1 | 59.59 ± 0.16 | 63.47 ± 2.07∗ | 65.02 ± 0.23∗ |
| S | 16.91 ± 1.20 | 14.03 ± 0.61 | 14.80 ± 2.36 | ||
| G2/M | 19.28 ± 1.87 | 19.77 ± 1.42 | 17.48 ± 3.22 | ||
| 48 h | G0/G1 | 58.49 ± 0.45 | 65.40 ± 1.10∗ | 69.61 ± 3.90∗ | |
| S | 16.45 ± 0.55 | 10.63 ± 0.25 | 13.64 ± 1.71 | ||
| G2/M | 22.28 ± 0.93 | 20.19 ± 0.04∗ | 15.66 ± 3.72∗∗ | ||
|
| |||||
| MDA-435 | 24 h | G0/G1 | 62.30 ± 1.12 | 61.99 ± 1.99 | 61.60 ± 0.64 |
| S | 14.84 ± 0.43 | 14.93 ± 0.24 | 14.87 ± 0.51 | ||
| G2/M | 19.90 ± 1.29 | 19.83 ± 2.04 | 18.88 ± 0.68 | ||
| 48 h | G0/G1 | 69.64 ± 1.18 | 70.64 ± 0.80 | 70.01 ± 1.85 | |
| S | 11.88 ± 0.89 | 11.30 ± 0.62 | 11.50 ± 0.53 | ||
| G2/M | 15.17 ± 1.03 | 15.52 ± 0.52 | 15.76 ± 0.83 | ||
The cell cycle phases and quantitative results are illustrated in accordance with the exposure time and PE concentration. The experiment is expressed as mean ± error standard. ∗ indicates significant differences from the control group (∗p < 0.05; ∗∗p < 0.01).