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. 2017 Jul 20;2(14):e94382. doi: 10.1172/jci.insight.94382

Figure 4. Microvascular alterations in pediatric and adult DCM.

Figure 4

(A) CD34 immunostaining demonstrating that, compared with donor controls, pediatric DCM specimens display increased microvascular density. In contrast, adult DCM patients have indistinguishable microvascular density compared with donor controls. Magnification 200×. (B) Quantification of microvascular density expressed as the percent of staining per 20× field. (C) Scatter plots showing that pediatric DCM patients display increased capillary density compared with donor controls across the spectrum of child ages. In contrast, capillary density did not differ between adult DCM specimens and donor controls at all ages examined. (D) CD34 staining stratified by age, revealing that microvascular density is increased in all pediatric groups. *P < 0.05 (Mann Whitney U test).