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. 2017 Jul 20;2(14):e94249. doi: 10.1172/jci.insight.94249

Figure 2. Enrichment of pluripotent-associated genes in pediatric dilated cardiomyopathy (DCM).

Figure 2

(A) GSEA enrichment plots showing an enrichment of mouse embryonic day 12.5 (E12.5) and E14.5 genes in pediatric DCM patients (heatmaps of enriched genes are provided in Supplemental Figure 3). These plots demonstrate the coexistence of embryonic-expressed genes in the context of pediatric DCM. (B) Schematic of the workflow used to unbiasedly identify all genes involved in signal transduction. KEGG database enrichment of pathways identified from the results of isolating all genes involved in signal transduction. See Table 2 for a list of the top 10 KEGG pathways identified.