Table 3.
Simple linear regression analysis using maximum dose (Dmax) and mean dose (Dmean) in sigmoid colon, anal sphincter and rectum associated with symptom groups. Bold indicates p ≤ 0.05. In the column of Symptom group, the number indicates each symptom group’s averaged factor score (and standard deviation in parenthesis).
| Sigmoid colon (the most caudal 4 cm) | Anal sphincter | Rectum | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Cohort | Symptom group | Predictor | Coefficient (β1) | p | Coefficient (β1) | p | Coefficient (β1) | p |
| POSTOP | Fecal leakage (A) 0.05(0.20) |
Dmax | 0.001 | 0.26 | 0.003 | 0.41 | 0.022 | 0.032 |
| Dmean | 0.001 | 0.67 | −0.003 | 0.039 | 0.003 | 0.020 | ||
| Fecal leakage (B) 0.26(0.57) |
Dmax | −0.0004 | 0.86 | 0.024 | 0.045 | 0.035 | 0.24 | |
| Dmean | −0.005 | 0.37 | 0.013 | 0.002 | 0.006 | 0.13 | ||
| Mucous 0.47(0.78) |
Dmax | 0.001 | 0.80 | 0.030 | 0.07 | 0.014 | 0.73 | |
| Dmean | 0.003 | 0.72 | 0.009 | 0.09 | 0.002 | 0.70 | ||
| Pain 0.43(0.61) |
Dmax | 0.003 | 0.25 | −0.013 | 0.30 | −0.005 | 0.89 | |
| Dmean | 0.007 | 0.21 | −0.002 | 0.71 | 0.010 | 0.031 | ||
|
| ||||||||
| EBRT | Defecation urgency 0.98(0.72) |
Dmax | 0.002 | 0.28 | 0.004 | 0.68 | 0.037 | 0.016 |
| Dmean | −0.0002 | 0.96 | 0.004 | 0.43 | 0.011 | 0.021 | ||
| Fecal leakage 0.57(0.99) |
Dmax | 0.002 | 0.39 | −0.012 | 0.42 | −0.015 | 0.47 | |
| Dmean | −0.001 | 0.79 | 0.003 | 0.61 | 0.009 | 0.17 | ||
| Mucous 0.33(0.64) |
Dmax | 0.001 | 0.38 | −0.001 | 0.92 | 0.028 | 0.040 | |
| Dmean | −0.003 | 0.42 | 0.002 | 0.56 | 0.007 | 0.11 | ||
| Pain 0.44(0.64) |
Dmax | −0.001 | 0.42 | −0.006 | 0.54 | 0.013 | 0.35 | |
| Dmean | −0.003 | 0.44 | −0.001 | 0.88 | 0.004 | 0.35 | ||