Skip to main content
. 2017 May 29;6(8):819–832. doi: 10.1016/j.molmet.2017.05.011

Figure 4.

Figure 4

Validation and characterization of NRK2KO mice. (A) mRNA expression of Nmrk2 in WT and NRK2KO quadriceps muscle, heart, and liver tissue. (B) Protein expression of NRK2 across metabolic tissues from WT and NRK2KO mice. (C) Whole body weight of 12 week old WT and NRK2KO mice. (D) Tissue weight of skeletal and cardiac muscle from 12 week old WT and NRK2KO mice. (E) Whole body weight of WT and NRK2KO mice following 6 weeks of endurance exercise training. (F) Tissue weight of skeletal and cardiac muscle from WT and NRK2KO mice following 6 weeks of endurance exercise training. (G) Muscle fiber cross-sectional area as a proportion of all fibers in WT and NRK2KO quadriceps. Fiber-type composition of TA (H) and soleus (I) skeletal muscle from WT and NRK2KO mice following 6 weeks of endurance exercise training. (All data n = 3–6).