Skip to main content
. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Curr Opin Hematol. 2017 May;24(3):159–166. doi: 10.1097/MOH.0000000000000328

Table 1.

Current gating strategies used to identify MEP, BFU-E and CFU-E by flow cytometry.

Progenitor population Species Cell surface markers Citation
Megakaryocyte-erythroid progenitor (MEP)
Mouse Lin flk2 IL7Rα c-kit+ FcgRII/III CD34 CD105+/− CD150+/− (13)
Human CD34+ CD38+ CD7+ CD10 FLT3 CD45RA MPL+/− (BAH1 clone) CD71+/− (10)
Human Lin CD34+ CD38+ IL-3R CD45RA CD71+/− CD105+/− (8)
Human Lin CD34+ CD38mid CD45RA FLT3 MPL+ CD36 CD41 (14)
Human Lin CD34+ CD38+ IL-3R CD45RA CD71 CD41 (9)
Burst forming unit-erythroid (BFU-E)
Mouse c-kit+ CD45+ Ter119 CD71low (15)
Mouse (stress) CD34 CD133 c-kit+ Sca-1+ (19)
Human IL-3R GPA CD34+ CD36 (17)
Human CD34+ CD123 CD71low TβRIIIlow/hi (18)
Human (stress) CD34 CD133 c-kit+ (19)
Colony forming unit-erythroid (CFU-E)
Mouse c-kit+ CD45 Ter119 CD71hi (15)
Mouse Lin c-kit+ Sca-1 IL-7Rα IL3Rα CD41 CD71+ (16)
Human IL-3R GPA CD34 CD36+ (17)