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. 2017 May 31;6(8):781–796. doi: 10.1016/j.molmet.2017.05.012

Figure 6.

Figure 6

Inducible adiponectin-Cre driven FASN deletion in adipocytes of mature mice does not enhance UCP1 expression and the thermogenic program in BAT. (A): Inducible deletion of adipocyte FASN does not affect UCP1 protein in BAT. Tissue lysates from controls and iAdFASNKO mice were immunoblotted for FASN, UCP1, or actin as indicated. (B): H&E staining of BAT from control and iAdFASNKO mice reveals no major morphological changes in BAT upon FASN deletion. Depicted are representative images of 5–7 mice per group. (C): qRT-PCR was performed for quantifications of indicated genes in BAT from controls and iAdFASNKO mice. N = 5–7 per group. *P < 0.05; ***P < 0.001.