Fig. 1.

Unsupervised hierarchical cluster analysis of scrotum and 46, XY labia majora fibroblasts (experimental set 1). The heatmap represents hierarchical clustering of 3,601 transcripts which had at least 80% interpretable data across the 16 microarrays and whose expression levels were at least twofold different from the mean expression level across all samples in at least four experiments. Transcripts are represented in rows and experiments in columns. Expression values per gene are centered by the mean log₂ Cy5/Cy3 normalized ration. Increasing red intensity corresponds to higher relative transcript levels compared to the mean expression level across all experiments. Increasing green intensity corresponds to relatively decreased transcript levels compared to the mean. The cluster dendrogram demonstrates the degree of relatedness (Pearson correlation) between the expression patterns of the 3,601 genes in the 16 fibroblast samples. The length of the arms of the dendogram reflects the degree of correlation between the samples normalized ratio.