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. Author manuscript; available in PMC: 2017 Jul 20.
Published in final edited form as: Clin Cancer Res. 2012 Apr 25;18(12):3366–3376. doi: 10.1158/1078-0432.CCR-11-3179

Figure 3.

Figure 3

Darinaparsin did not radiosensitize normal radiosensitive tissues. A, Balb/C mice were treated with darinaparsin (100 mg/kg, i.p., 4 hours) alone, total body irradiation (IR) alone, or IR following darinaparsin (IR/DPS). Each group (N = 8) comprised 2 subgroups (N = 4). Each subgroup was retroorbitally bled alternatively (every other week) and counted for WBC, RBC, HGB, and platelets. B, Balb/C mice were divided into 4 groups, including untreated control (CON), darinaparsin (100 mg/kg, i.p.), IR, and IR following 4 hours darinaparsin treatment (IR/DPS). N = 3 per group. The intestinal samples were collected 3.5 days after IR, and viable crypts/cross section were quantified. Data presented are from duodenum samples. *, P < 0.05 versus CON. Data are representative of 3 independent experiments.